For in-vitro research use only. Not for human consumption.
LL37
LL-37 is the only human cathelicidin, a 37-amino acid alpha-helical peptide processed from the precursor protein hCAP18. It exhibits broad-spectrum antimicrobial activity through membrane disruption and also functions as an immunomodulator, chemokine, and angiogenesis factor. Research examines its roles in innate immunity, wound healing, and biofilm disruption.
LL37 definition
LL-37 is the active 37-amino-acid C-terminal cathelicidin antimicrobial peptide derived from the human cathelicidin precursor protein hCAP-18. Research models examine its broad-spectrum antimicrobial activity, role in innate immunity, and interactions with mammalian cell membranes. The peptide is alpha-helical in membrane environments. Research use only. Supplied by Nexus Laboratory with batch-level certificate of analysis documenting HPLC purity, mass spectrometry identity, and endotoxin screening.
No sequence is listed in the current catalog record for this product.
- CAS
- 154947-66-7
- MW
- 4493.33 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C205H340N60O53
- Purity
- 99.81%
- Form
- Lyophilized powder
- Class
- Cathelicidin Antimicrobial Peptide (CAMP)
Reconstitution calculator
Estimate vial concentration and aliquot volume from the selected vial mass, solvent volume, and target research amount.
Calculations are for lab planning only and do not replace the product COA, protocol requirements, or qualified professional review. Confirm solvent compatibility before use.
Compound details.
- CAS Number
- 154947-66-7
- Molecular Weight
- 4493.3 g/mol
- Class
- Cathelicidin antimicrobial peptide
- Sequence length
- 37 residues
- Structural class
- Alpha-helical amphipathic peptide
Research context.
Studied in preclinical research models examining antimicrobial peptide pharmacology, innate-immune signaling research, membrane-interaction research, and wound-healing-related innate-immunity research models. Research use only.
Verification standard.
Every Nexus Laboratory batch ships with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin screening — verified by third-party laboratory testing and publicly archived. Review Nexus lab verification.
LL37 is part of the Nexus Healing & Recovery catalog. Tissue repair, immune modulation, and recovery-oriented research peptides. Each listed variant is priced from the consolidated Nexus catalog and intended for qualified research use only.
TODO-COPY: replace with real compound-specific narrative.
The chemistry.
37-amino acid human cathelicidin antimicrobial peptide
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: LL-37 5mg
- Classification: Cathelicidin Antimicrobial Peptide (CAMP)
- Structural Description: 37-amino acid human cathelicidin antimicrobial peptide
- CAS Number: 154947-66-7
- Molecular Weight: 4493.33 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
HPLC trace preview.
Related research compounds
Same category, mechanism overlap, and common research stack pairings.
LL37 research FAQ.
What is LL37 used for in research?
LL37 is supplied for controlled in-vitro research workflows in the Healing & Recovery category. It is not labeled for human or veterinary use.
Is LL37 HPLC verified?
LL37 is listed with Nexus lab verification. Current catalog records show 99.81% purity context where batch COA data is available.
Which LL37 sizes are available?
Current Nexus variants include 5mg.
Does LL37 include a COA?
Yes. The current Nexus record links LL37 to batch NEX-LL37-2026-0050.