For in-vitro research use only. Not for human consumption.
Semaglutide
Semaglutide is a modified GLP-1 analog engineered with an albumin-binding fatty acid side chain that extends its half-life in research models. It binds and activates the GLP-1 receptor, which plays a central role in glucose homeostasis and appetite regulation pathways.
Semaglutide definition
Semaglutide is a modified GLP-1 analog engineered with an albumin-binding fatty acid side chain that extends its half-life in research models. It binds and activates the GLP-1 receptor, which plays a central role in glucose homeostasis and appetite regulation pathways.
No sequence is listed in the current catalog record for this product.
- CAS
- 910463-68-2
- MW
- 4113.58 g/mol
- Sequence
- Not listed
- Half-life
- Discussed in research notes
- Formula
- C187H291N45O59
- Purity
- 99.52%
- Form
- Lyophilized powder
- Class
- GLP-1 Receptor Agonist
Reconstitution calculator
Estimate vial concentration and aliquot volume from the selected vial mass, solvent volume, and target research amount.
Calculations are for lab planning only and do not replace the product COA, protocol requirements, or qualified professional review. Confirm solvent compatibility before use.
Compound details.
- CAS Number
- 910463-68-2
- Molecular Weight
- 4113.58 g/mol
- Molecular Formula
- C₁₈₇H₂₉₁N₄₅O₅₉
- Class
- GLP-1 Receptor Agonist
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
One of the most extensively studied peptides in modern metabolic research, Semaglutide has been the subject of the STEP, SUSTAIN, and PIONEER clinical trial programs. Published data spans applications in glycemic control, cardiovascular outcomes, and metabolic signaling. It remains a benchmark compound for GLP-1 receptor studies in laboratories worldwide.
Verification standard.
Every Nexus Laboratory batch ships with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin screening — verified by third-party laboratory testing and publicly archived. Review Nexus lab verification.
Semaglutide is part of the Nexus GLP-1 & Metabolic catalog. GLP-1, amylin, and multi-agonist metabolic research peptides. Each listed variant is priced from the consolidated Nexus catalog and intended for qualified research use only.
TODO-COPY: replace with real compound-specific narrative.
The chemistry.
31-amino acid GLP-1 analog with a C-18 fatty diacid chain
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: Semaglutide
- Classification: GLP-1 Receptor Agonist
- Structural Description: 31-amino acid GLP-1 analog with a C-18 fatty diacid chain
- CAS Number: 910463-68-2
- Molecular Weight: 4113.58 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
HPLC trace preview.
Related research compounds
Same category, mechanism overlap, and common research stack pairings.
Semaglutide research FAQ.
What is Semaglutide used for in research?
Semaglutide is supplied for controlled in-vitro research workflows in the GLP-1 & Metabolic category. It is not labeled for human or veterinary use.
Is Semaglutide HPLC verified?
Semaglutide is listed with Nexus lab verification. Current catalog records show 99.52% purity context where batch COA data is available.
Which Semaglutide sizes are available?
Current Nexus variants include 2mg, 5mg, 10mg, 15mg, 20mg, 30mg.
Does Semaglutide include a COA?
Yes. The current Nexus record links Semaglutide to batch NEX-SEMAGLUTIDE-2026-0076.