For in-vitro research use only. Not for human consumption.
PT-141
PT-141 (Bremelanotide) is a cyclic heptapeptide metabolite of Melanotan II. It activates melanocortin receptors MC3R and MC4R with relative selectivity over MC1R. Research focuses on its central nervous system melanocortin signaling, particularly in hypothalamic pathways regulating sexual arousal and behavior.
PT-141 definition
PT-141 (Bremelanotide) is a cyclic heptapeptide metabolite of Melanotan II. It activates melanocortin receptors MC3R and MC4R with relative selectivity over MC1R. Research focuses on its central nervous system melanocortin signaling, particularly in hypothalamic pathways regulating sexual arousal and behavior.
No sequence is listed in the current catalog record for this product.
- CAS
- 189691-06-3
- MW
- 1025.18 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C50H68N14O10
- Purity
- 99.74%
- Form
- Lyophilized powder
- Class
- Melanocortin Receptor Agonist (MC3R/MC4R Selective)
Reconstitution calculator
Estimate vial concentration and aliquot volume from the selected vial mass, solvent volume, and target research amount.
Calculations are for lab planning only and do not replace the product COA, protocol requirements, or qualified professional review. Confirm solvent compatibility before use.
Compound details.
- CAS Number
- 189691-06-3
- Molecular Weight
- 1025.18 g/mol
- Molecular Formula
- C₅₀H₆₈N₁₄O₁₀
- Class
- Melanocortin Receptor Agonist (MC3R/MC4R Selective)
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
The branded clinical product Vyleesi is approved for hypoactive sexual desire disorder (HSDD) in adult women; Apex's research-grade material is supplied for in-vitro research only. Published in Journal of Sexual Medicine and Journal of Urology. Research examines CNS melanocortin signaling as distinct from peripheral melanogenesis pathways.
Verification standard.
Every Nexus Laboratory batch ships with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin screening — verified by third-party laboratory testing and publicly archived. Review Nexus lab verification.
PT-141 is part of the Nexus Sexual Health catalog. PT-141, VIP, and related signaling research compounds. Each listed variant is priced from the consolidated Nexus catalog and intended for qualified research use only.
TODO-COPY: replace with real compound-specific narrative.
The chemistry.
Cyclic 7-amino acid peptide (Bremelanotide), metabolite of Melanotan II
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: PT-141 10mg
- Classification: Melanocortin Receptor Agonist (MC3R/MC4R Selective)
- Structural Description: Cyclic 7-amino acid peptide (Bremelanotide), metabolite of Melanotan II
- CAS Number: 189691-06-3
- Molecular Weight: 1025.18 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
HPLC trace preview.
Related research compounds
Same category, mechanism overlap, and common research stack pairings.
PT-141 research FAQ.
What is PT-141 used for in research?
PT-141 is supplied for controlled in-vitro research workflows in the Sexual Health category. It is not labeled for human or veterinary use.
Is PT-141 HPLC verified?
PT-141 is listed with Nexus lab verification. Current catalog records show 99.74% purity context where batch COA data is available.
Which PT-141 sizes are available?
Current Nexus variants include 10mg.
Does PT-141 include a COA?
Yes. The current Nexus record links PT-141 to batch NEX-PT-141-2026-0071.