For in-vitro research use only. Not for human consumption.
MOTS-c
MOTS-c is part of the Nexus Longevity & Cellular Health catalog. Mitochondrial, senolytic, and cellular health research compounds. Each listed variant is priced from the consolidated Nexus catalog and intended for qualified research use only.
MOTS-c definition
MOTS-c is a 16-amino acid peptide encoded in the mitochondrial 12S rRNA gene. It activates AMPK signaling and regulates cellular metabolism, folate-methionine cycling, and de novo purine biosynthesis. MOTS-c can translocate to the nucleus in response to metabolic stress, acting as a mitochondrial-nuclear retrograde signal.
No sequence is listed in the current catalog record for this product.
- CAS
- N/A
- MW
- 2174.7 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- Not listed
- Purity
- Not listed
- Form
- Not listed
- Class
- Longevity & Cellular Health
Reconstitution calculator
Estimate vial concentration and aliquot volume from the selected vial mass, solvent volume, and target research amount.
Calculations are for lab planning only and do not replace the product COA, protocol requirements, or qualified professional review. Confirm solvent compatibility before use.
Compound details.
- Molecular Weight
- 2174.7 g/mol
- Molecular Formula
- C₁₀₀H₁₆₃N₂₇O₂₂S
- Class
- Mitochondrial-Derived Peptide (MDP)
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
Discovered by Dr. Pinchas Cohen's lab at USC and published in Cell Metabolism (2015). Research examines its role as a mitochondrial-encoded hormone (mitokine) regulating systemic energy homeostasis, insulin sensitivity, and exercise-responsive metabolic signaling.
Verification standard.
Every Nexus Laboratory batch ships with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin screening — verified by third-party laboratory testing and publicly archived. Review Nexus lab verification.
MOTS-c is part of the Nexus Longevity & Cellular Health catalog. Mitochondrial, senolytic, and cellular health research compounds. Each listed variant is priced from the consolidated Nexus catalog and intended for qualified research use only.
TODO-COPY: replace with real compound-specific narrative.
The chemistry.
Static molecular fallback shown because this catalog record does not include a sequence suitable for the amino-acid viewer.
HPLC trace preview.
Related research compounds
Same category, mechanism overlap, and common research stack pairings.
MOTS-c research FAQ.
What is MOTS-c used for in research?
MOTS-c is supplied for controlled in-vitro research workflows in the Longevity & Cellular Health category. It is not labeled for human or veterinary use.
Is MOTS-c HPLC verified?
MOTS-c is listed with Nexus lab verification. Current catalog records show batch-specific purity context where batch COA data is available.
Which MOTS-c sizes are available?
Current Nexus variants include 10mg, 40mg.
Does MOTS-c include a COA?
Yes. The current Nexus record links MOTS-c to batch NEX-MOTS-C-2026-0055.