For in-vitro research use only. Not for human consumption.
SS-31
SS-31 (Elamipretide) is a cell-permeable tetrapeptide that selectively concentrates in the inner mitochondrial membrane by binding cardiolipin. This interaction stabilizes cytochrome c and optimizes electron transport chain function, reducing mitochondrial ROS production. It is the most studied mitochondria-targeted peptide.
SS-31 definition
SS-31 (Elamipretide) is a cell-permeable tetrapeptide that selectively concentrates in the inner mitochondrial membrane by binding cardiolipin. This interaction stabilizes cytochrome c and optimizes electron transport chain function, reducing mitochondrial ROS production. It is the most studied mitochondria-targeted peptide.
No sequence is listed in the current catalog record for this product.
- CAS
- 736992-21-5
- MW
- 640.77 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C32H49N9O5
- Purity
- 99.54%
- Form
- Lyophilized powder
- Class
- Mitochondria-Targeted Antioxidant Peptide
Reconstitution calculator
Estimate vial concentration and aliquot volume from the selected vial mass, solvent volume, and target research amount.
Calculations are for lab planning only and do not replace the product COA, protocol requirements, or qualified professional review. Confirm solvent compatibility before use.
Compound details.
- CAS Number
- 736992-21-5
- Molecular Weight
- 640.77 g/mol
- Molecular Formula
- C₃₂H₄₉N₉O₅
- Class
- Mitochondria-Targeted Antioxidant Peptide
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
Developed by Dr. Hazel Szeto. Published in Clinical Pharmacology & Therapeutics and JACC. Clinical trials have investigated it in heart failure (TANGO), Barth syndrome, and age-related mitochondrial dysfunction. A key research tool for studying mitochondrial medicine.
Verification standard.
Every Nexus Laboratory batch ships with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin screening — verified by third-party laboratory testing and publicly archived. Review Nexus lab verification.
SS-31 is part of the Nexus Longevity & Cellular Health catalog. Mitochondrial, senolytic, and cellular health research compounds. Each listed variant is priced from the consolidated Nexus catalog and intended for qualified research use only.
TODO-COPY: replace with real compound-specific narrative.
The chemistry.
4-amino acid peptide (D-Arg-Dmt-Lys-Phe-NH2), also known as Elamipretide/Bendavia
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: SS-31
- Classification: Mitochondria-Targeted Antioxidant Peptide
- Structural Description: 4-amino acid peptide (D-Arg-Dmt-Lys-Phe-NH2), also known as Elamipretide/Bendavia
- CAS Number: 736992-21-5
- Molecular Weight: 640.77 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
HPLC trace preview.
Related research compounds
Same category, mechanism overlap, and common research stack pairings.
SS-31 research FAQ.
What is SS-31 used for in research?
SS-31 is supplied for controlled in-vitro research workflows in the Longevity & Cellular Health category. It is not labeled for human or veterinary use.
Is SS-31 HPLC verified?
SS-31 is listed with Nexus lab verification. Current catalog records show 99.54% purity context where batch COA data is available.
Which SS-31 sizes are available?
Current Nexus variants include 10mg, 50mg.
Does SS-31 include a COA?
Yes. The current Nexus record links SS-31 to batch NEX-SS-31-2026-0083.